Nanobiotechnology-laboratory_en:
Reference: 2024-1-TCB-NANOBIOTECH
Location: Ispra, (Italy)
Deadline date: 21 May 2024, 23:59 (CEST)
The Nanobiotechnology Laboratory features state-of-the-art equipped facilities designed to foster interdisciplinary studies. A special emphasis lies on characterisation of nanomaterials, micro-nanoplastics, nanomedicines, advanced materials and their interactions with biological systems, as well as on the detection, identification and characterisation of nanomaterials in food and consumer products.
Hands-on training on detection and characterisation of micro(nano)plastics in media contributing to human exposure (such as food, drinking water). Topics will include sampling from drinking water and the subsequent use of established instrumental methods such as micro Fourier transform infrared, micro Raman and pyrolysis– gas chromatography mass spectroscopy for microplastic detection and characterisation. To complement the hands-on training in the analysis of microplastics, participants will get an overview of key advanced nanomaterials characterisation tools highlighting their potential application to the challenges of analysing nanoplastics.
Hands-on training on detection and characterisation of nanomaterials in a selection of matrices (e.g. food) and their interactions with biological systems. Topics will include techniques for nanomaterial sizing, nanomaterials hydrophobicity determination, detection of nanomaterials in food and measurements of nanomaterials interactions in biological systems. The training will include the use of instrumentation such as asymmetric flow field flow fractionation coupled to multiple detectors, dark field microscopy, single particle and single cell inductively coupled plasma mass spectrometry. New approach methodologies mimicking the human intestinal barrier in vitro will be exposed to innovative nanomaterial and interactions will be measured by assessing trans-epithelial electrical resistance and confocal fluorescence microscopy. This topic will include an introduction to 3D cell models and bioprinting.
Hands-on training on the characterisation of nanomedicines (including liposomal products, Lipid Nanoparticles-mRNA) for the detection, diagnostics and treatment of diseases. The topics will include the measurement of key properties of nanomedicine products such as size, composition, encapsulation efficiency, toxicity and potency with a set of complementary techniques (dynamic light scattering, asymmetric flow field flow fractionation, liquid chromatography, analytical ultracentrifugation, immunoassays, surface plasmon resonance, or microarray technology). This topic will include an introduction to 3D cell models and bioprinting.
The training will be held in Autumn 2024 and will last 5 days. You can get more information here
The JRC may provide a financial or in-kind contribution to support Users to cover their costs of travel and subsistence (T&S) related to the User Stay Days, subject to the availability of funds, personnel and other resources to Users from User Institutions located in a country eligible for the Widening Participation and Spreading Excellence actions under the Horizon Europe programme.
Contact the research infrastructure at JRC-OPEN-NANOBIOTECH@ec.europa.eu to assess feasibility aspects in case you request a topic different from the list of Training and Capacity Building topics for the Nanobiotechnology laboratory.
The proposal should be submitted to JRC-RI-TRAINING-CB@ec.europa.eu by 21st of May 2024