Scientific Outputs
This action proposes to carry out research in open ended contact probe (OECP) technique to lay out foundation work for development of two new applications: an automated surgical margin detection device for breast cancer treatment and an automated microwave biopsy probe for breast cancer diagnosis. While the envisioned applications require a single and highly accurate measurement, OECP technique suffers from high error and low repeatability dielectric property measurements. The error mostly stems from the current mathematical approach utilized for the dielectric property retrieval which may converge to local minimum and can magnify the measurement set-up based errors. This research will first target the existing error by proposing robust mathematical retrieval approaches. Next, application based modifications will be investigated with new probe structures. Finally, further error minimization will be achieved by introducing classification algorithms. Developed techniques will be validated with animal experiments. The outcomes of this research will greatly contribute to the innovation of new medical devices that can be utilized for breast cancer, representing one of the most commonly diagnosed cancer type among women.
Tackling ‘grand’ or societal challenges
Breast cancer is second cause of cancer related deaths among women. Today, about 12% of women are at high risk of breast cancer development during their lifetime. The project will contribute to breast cancer research through development of medical devices that can be utilized during treatment and diagnosis of breast cancer.
The improved exercise of professional skill
Through the project, the researcher will gain an expertise on microwave dielectric spectroscopy with open ended contact probes. More importantly, the interdiciplinary nature of the project will enable the researcher expand her network and thus leading submission of new projects.
Human capital development
This project will allow the researcher to become independent by extending her network, publication/grant track record, skill sets, and more importantly, through joining an innovation oriented host organization, the researcher will gain expertise in phases that enables the research to be transformed into innovation.
